Share the Load - quests covered
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As at version 2.1

1. Daedric quests
- The House of Horrors - Removes Vigilant Tyranus from the game.
- A Daedra's Best Friend - Stops people in Falkreath from asking about a dog. Barbas is back with Vile.
- The Mind of Madness - Removes Dervenin.
- Pieces of the Past - Removes courier message, and suppresses intro scene.
- The Whispering Door - Prevents you hearing the rumour about the jarl's kids, without which the quest will never start.
- The Black Star - Removes Aranea from the game.
- Boethiah's Calling - Prevents attackers carrying Boethia books.
- Ill Met by Moonlight - Removes Sinding, and you won't see the girl's funeral in Falkreath.
- The Taste of Death - Removes Verulus, Eola and related rumours. (I would have liked to kill all the cannibals, but can't do that.)
- The Only Cure - Removes 'Afflicted refugees'.
- The Cursed Tribe - No giant attacks. If you get into the orc stronghold, Yamarz is dead and Gularzob is in charge.
- A Night to Remember - Removes Sam
- Waking Nightmare - "The nightmares have stopped. Don't suppose you'd know anything about that?" Removes Earandur.
- The Break of Dawn - Meridia's Screaming Beacon will never spawn (unless it already has), and her statue won't talk.

2. Miscellaneous quests
- Blood on the Ice - The killer is gone, Susanna is still alive.
- Lights Out! - Jaree-Ra and Deeja removed from the game.
- The Blessings of Nature - Gildergreen has been replaced with a sapling.
- Unfathomable Depths - Removes From-Deepest-Fathoms from the game.
- In My Time of Need - Removes Saadia, and the Alik'r wilderness encounters.
- Delayed Burial - Removes Cicero and his cart from the road north of Whiterun. (Loreius and his family are fine. If you join the Dark Brotherhood later, Cicero will show up at the usual stage. He won't recognise you.)
- The Forsworn Conspiracy - Removes Eltrys, Weylin, Margret, Nepos and Madenach. Thonar is dead, and serve him right.
- Laid to Rest - The burned house mystery is solved, Alva and Movarth are gone. WARNING: if you want to become Thane of Hjaalmarch, you'll need to find some other way to gain the Jarl's favour. Standard quests won't do it.
- Promises to Keep - Removes Louis from the game. Sibbi is set to non-essential. (Just in case some homicidal lunatic breaks into the jail. You never know.)
- Missing in Action - you won't be asked to rescue Thorald.

3. Faction quests
- Joining the College of Winterhold - Lets you simply walk into the college without joining it. If you want to join later, talk to Mirabelle.
- Innocence Lost - Grelod is dead, and you won't hear rumours about Aventus in Windhelm.
- Destroy the Dark Brotherhood! - The Dark Brotherhood is destroyed. Note, this doesn't make any difference in-game - you'll still encounter the assassins from time to time - but that's part of the base game.
- Tending the Flames - Skips the Bards' College entrance quest. You can still take the other tat-collecting quests from the college.

4. DLC quests
- Unearthed (Kolbjorn Barrow) - Deletes Ralis from the game. You can't explore the barrow.
- March of the Dead - Ash spawn attacks on Raven Rock have been taken care of. Note: skipping this quest *and* 'The Final Descent' will also skip 'Served Cold', and you'll never own a home in Raven Rock.)
- The Final Descent - Raven Rock mine has been reopened without your help. Note: skipping this *and* 'March of the Dead' will automatically skip 'Served Cold', and you'll never own a home in Raven Rock.
- Served Cold - The Severins have been dealt with. Note: if you skip this quest, obviously you don't get Severin Manor.