Here are a few patches for Through the Valleys Mod Guide that you might find useful.

Oblivion Content Restoration Project TtV Patch (TtV only)
A patch that fixes level cap and balance between Oblivion Content Restoration Project and Through the Valleys.

NAO - Even Brighter Nights and Closer Fog Fix (TtV and Vanilla)
Fix for NAO - Even Brighter Nights and Closer Fog, now enemy will detect you at night

NAO - Brighter Nights and Closer Fog Fix (TtV and Vanilla)
The same, but the nights are 30% darker.

Creatures Attack Reach Fix (TtV only)
The hit range fix for some creatures (wolf, zombie, deer, etc) that just couldn't hit you, even if you backed away slightly (This is still not enough, but better than nothing).

NPCsTravel - TtV patch (TtV and Vanilla + Oblivion Character Overhaul)
Removes all high level equipment from NPCs Travel, respawn, inability to loot some NPCs, reduces the merchants gold, and removes the ability to sell them any type of items.

Ayleid coin icon (TtV and Vanilla)
Deleted, I recommend using this mod instead.

Sneak Tweak (TtV and Vanilla)
In my testing, these are pretty good settings, sneak still looks like vanilla. Light mult has been increased by 2, the degree of importance has been reduced by 5, but you can still easy hide in the shadows even at low skill levels.

No lockpick auto attempt (TtV and Vanilla)
FOR DEFAULT UI! Just removes the auto attempt. This will force you to work a little with the skeleton key. Drop it in data.