This small plugin will boost your game!
-Video memory cleaner
-Cell Buffers cleaner
-NPC AI fix

Cleaners work before fast travel (when you open map menu) and on cell change
NPC AI fix its a bug when Actor's AI not work when player is near, its happen in heavy modded games.

You need some stuff for it
-OBSE
-Oblivion Reloaded 6.3
-SDR

Then in OblivionReloaded.ini find
[Purger]
Enabled=1
Time=0
PurgeTextures=1
PurgeCells=1
Key=88

It must be like this, you can put PurgeCells to 0 if want only textures purger.