What are the other conflicts? I've only ever noticed problems at Ft Hagen. I did have to fix General Atomics interior in another patch, but that was due to an interior lighting mod I was using at the time.
Yes. For some reason, it completely breaks "Follow Player" and "Escort Player" AI packages while active, so a few quests won't run right. In those quests where either an NPC needs to follow you or you need to follow an NPC, use the in-game options to disable spawning and remove already spawned actors. Other than that, it's fine for a normal game. It will murder your framerate in some places if you add a large number of NPCs, but that's the game engine's fault, not the mod.
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I moved on to Endless Warfare from WotC because of performance issues.
And this mod fixes problem of EW perfectly.