With the Intimidation Perk, you will be able to:

- Pacify Enemies
- Cuff them with Handcuffs
- Search their Inventory
- Inject them with dirty psycho so that they will fight for you
- Interrogate them in order to get the location of their allies
- Put a detonatable collar on them and give them commands

Those actions can be done by activating the NPC. The different actions mentioned above will show up depending on the distance to the NPC, if you sneak and if you aim through your iron sights or not.

So if you sneak before a pacified enemy, and stand very close to them, you can cuff them for example.