Detailed Information: Vile Concoctions
Vile Concoctions Perks
Grenadier
Can craft and throw grenades
You can either throw them manually, without a cooldown, (IE using up hand slots)
Or you can throw them via hotkey, which (optionally) uses a cooldown
Sapper
Can craft and deploy mines
Mines come in 2 Qualities: Standard and Dwemer
Dwemer ones are twice as potent but require rarer materials
Artificer
Can craft explosive arrows
Toxicity
Potion last thirty times longer.
Alchemical effects increase toxicity.
Start with a maximum toxicity of 3.
Hearty Thirst
Restore potions are four times as effective.
Drinking potions causes cooldowns with a base duration of 10 seconds.
Concentrated Poison
+1 poison doses for every 25 alchemy levels
Gastromancy
Player no longer regenerates health
Eating food heals 15 health
Gain +50 Health for every 10 overall levels
Capped at +400 Health
Alcohest
Gain the ability to mark up to 5 potions as signature potions.
Signature potions can be restocked to 4 using alcohest when the player waits.
At least one signature potion must exist in order to "refill".
Lethal Dose
Poison gains a sneak multiplier scaling with alchemy level. Up to 3x at level 100 alchemy
Aromatics
Drinking restoration potions also restore nearby allies
Magnitude equals half of alchemy level
Desensitization
Fortify potions no longer trigger cooldowns
Efficient Filtering
Gain the optional ability to make up to 10 times as many potions from a set of ingredients, but with a lower magnitude.
Mithridization
+1 Maximum Toxicity. +50 Poison Resist.

Toxicity Engine
Each alchemy effect with a duration increases toxicity by 1
A potion with 2 effects increases toxicity by 2 for example
Instant potions do not trigger toxicity (this is intentional, so you can still drink restore potions and poison cures at high toxicity and such)
Toxicity lasts for as long as the potion effect
Going over your toxicity limit purges all positive alchemical effects, and triggers an overdose reaction
Overdose penalties can range from attribute damage, reduced movement speed, and or vomiting (adjustable/toggleable via slider)
Enemy poison you can increase your toxicity, so beware when fighting poisonous enemies

Potion Cooldown Engine
Does what it says on the tin, if you try to drink a potion during cooldown, nothing happens and your potion is refunded
Cooldown duration is adjustable via slider

Alternative Leveling
You can now gain experience from drinking fortify potions, scaled to the potion's duration
You can now gain experience from hitting enemies with explosives
You can now gain experience from using the explosive materials extractor
You can now gain experience from crafting explosives

Potion/Poison Balance Sliders
Slider for potion duration (Recommend increasing this to at least 4x, with the toxicity engine)
Slider for poison magnitude scaling with alchemy level (Recommend increasing this to 2x or higher)
Slider for potion magnitude scaling with alchemy level (Recommend increasing this to 2x)
Slider for explosives magnitude scaling with alchemy level (Recommend increasing this to 2x or higher)
Slider for poison sneak mult (Recommend increasing this to 2x)
Slider for explosives sneak mult (Recommend increasing this to 2x)
Toggleable option to allow fortify alchemy magical effects to also affect potions and poisons (recommend enabling this)

How To Blow Sh*t Up (IE use explosives)
Step 1: Craft your explosives tools (IE a mortar and pestle) at a forge
Step 2: Use the the mortar from your inventory, then exit the inventory
Step 3: Select the "Extractor" option
Step 4: Deposit potions, alcohols, ingredients (and rarely other items work too) into the extractor in hopes of extracting explosive materials
Step 5: Access the mortar again, but this time select the option to craft explosives
Step 6: Use the crafting menu
Step 7: Grenades/Mines can be used like scrolls to throw them manually. Alternatively you can use the quickthrow hotkey configured from the MCM menu, if you want to utilize a cooldown and or avoid using up a hand slot when throwing grenades.