Download the MEAExplorerWV from here: https://github.com/zeroKilo/MEAExplorerWV
Unpack the zip, optimally into your game folder.
Copy both files from the AnselSDK64/Release directory directly into your game directory. Replace, when prompted. This step is apparently currently necessary to enable modding. Without it your game will not start with the modified files.
Launch the MEAExplorerWV.exe in MEAExplorerWV/Release
Right click on "FS" on the left. Choose "Load FS" and direct it to your "MassEffectAndromeda.exe" in your game directory. Wait a moment for it to load.
Click on "Mod Manager" at the top
In the new window click on "Mods" and "Load List"
Choose your .meamod file
Click on "Mods" and "Run all"
Close the MEAExplorerWV and run the game

If you get an error "ERROR: Plugin 'SHA1 Export/Import' not found!" when clicking Run All, try this:

QUOTE
In the folder MEAExplorerWV\Release, find all dll files also the ones in sub folders. Right click on each dll and select properties. At the bottom of the properties menu, you will see a button called "unblock" click it then click apply followed by ok. Do this for all dll files. Then run MEA Explorer
Thanks CultKiller for that one!
And:
QUOTE
When you download MEAExplorerWV-master.zip, BEFORE you unzip it, right click on it, click Properties, and check "Unblock" at the bottom. Unzipped files inherit the "block" status of the parent zip, so be sure to do this first if you're getting the error as I did above.
Thanks JBak