1) Description: 
This is a Patcher for xEdit / SSEEdit that creates a new .esp-Patch, which removes all Spell Tomes from your Skyrim game.

It has been tested with Skyrim SSE v1.5.97, Mod Organizer 2 v2.2.1 and SSEEdit v4.0.3, but should also work for Oldrim or Skyrim VR and other versions.

The Patcher removes Spell Tomes from Form Lists and Leveled Lists (i.e. Vendor Inventories, Loot Lists), Containers (i.e. Chests) and References (i.e. Spell Tomes placed in Cells and in Worldspace), by searching for the term 'Spell Tome' or 'SpellTome' in these records.

Note: Quest Records are skipped to avoid breaking the Quests.

This is the first draft of the Patcher. If you add this patch to your game and find Spell Tomes (except for Quest Spell Tomes) that did not get removed properly, let me know.
 
This Patcher was created for Spell Research, where there are other means to learn new spells apart from Spell Tomes.

It is recommended to run the Patcher when you have finalized your mod list and are about to start a new playthrough. If you add or remove mods, run the Patcher again to make sure, all of your current mods are taken into account.

2) Installation:
Download and install the latest version of xEdit / SSEEdit

Copy the two files: "No_Spell_Tomes_Patcher.pas" and "Add_Masters_By_Signature_No_Spell_Tomes.pas" into the "Edit Scripts" subfolder, in the directory where you've installed SSEEdit.

3) Usage:
Run xEdit / SSEEdit and load your whole mod list. When the background loader has finished, select all loaded mods, then right-click on any mod and choose "Apply Script..."  from the context menu. Choose the script "No_Spell_Tomes_Patch" from the drop-down menu. You will be prompted to enter the name of the new .esp-Patch file that will be created from this script. Choose a name such as "No_Spell_Tomes_Patch" (without the .esp ending) or something to your liking. 
Note that none of your existing mods will be changed by the Patcher, but a new .esp file will be created, which contains all the changes. When the Patcher is finished, save the new .esp-Patch file and close SSEEdit. Make sure to place the patch relatively low in your load order to make sure that the changes of the Patch are not overwritten by any other mods.

4) If you have too many mods:
If you have more than 254 active mods and light plugins (ESL-flagged .esps), then you will get an error message in SSEEdit when you run the above script: "Only 0 of 1 masters could be added. Master list now contains 253 entries and is full."

If this is the case, then you first need to create a new Masters .esp file as follows: (see this manual - thanks to Fayhe for this solution).

Run xEdit / SSEEdit and load your whole mod list. When the background loader has finished, select all loaded mods, then right-click on a mod and choose "Apply Script..."  from the context menu. This time, choose the script "Add_Masters_By_Signature_No_Spell_Tomes" from the drop-down menu instead. You will be prompted to enter the name of the new Masters .esp-file that will be created from that script. Choose a name such as "No_Spell_Tomes_Masters" (without the .esp ending) or something to your liking. 

Save the new Masters .esp-Patch file and close SSEEdit. This Masters .esp-Patch file will only include mods that contain the relevant records that need to be patched.

Repeat the steps from 3) again, but instead of loading your whole mod list, only load the newly created Masters .esp-file to be loaded (SSEEdit will automatically load all other mods that contain the records that need to be patched as well). If the step 3) was successful and the "No_Spell_Tomes_Patch" was created, you can delete the Masters .esp-Patch file, as it is not longer required. Should you still exceed the 254 mod limit, then you will need to divide your mod list into multiple chunks and run the Patcher for each chunk.

Credits:
- Merrymac for the mod "No Spell Tomes as Loot or From Vendors" that got me started
- ElminsterAU for SSEEdit
- Fayhe for the solution to reduce Masters