So, with the massive amount of third party software needed now. Here's a list of stuff I've found to be useful.

B.A.E - Bethesda Archive Extractor
(Open those pesky Bs2 archives that are too good for 7-zip compression.)

MultiXwM - Xwm converter
(Turn those pointless xwm files into .wav format that you can edit and such.)

Material Editor - Material Editor
(Because in spite of numerous written threats, .bgsm files are now a thing. I must now remain at least 200 feet away from Todd Howard at all times.)

Wavosaur - Audio Editor
(Fallout 4 wave files rely on loop markers to do certain stuff. Wavosaur is great for this, as well as quick edits.)

Audacity - Audio Editor
(Good for larger audio projects that involve mixing and generating sounds.)

7-Zip File Manager
(It's like Nexus Mod Manager for clever people. Great for compressing big mods and cut down large amounts of download time. A hundred times better than WinRAR, seriously.)