Most of these solutions will involve using the script extender console, so please install that version. Please let me know if there's anything else I should add on to here.

DURGE Duel (if you know, you know)
Someone listed these steps. I've never tried them, maybe it'll work for others.

1. Uninstall all versions of appearance edit completely and update script extender
2. load into the save, and make sure you're NOT near Orin, go OUTSIDE of
the Bhaal temple where Scleritas is. Save the game, exit. 
3. Reinstall the Appearance edit mod (MAIN ONE ONLY)
4. Reload the save that you made before. 
5. Sneak, and resculpt your character again into Dark Urge and take all the leveling choices you made
6. Proceed with the resculpting as per-normal. MAKE SURE TO LET THE MESSAGE TELL YOU WHEN TO PRESS ACCEPT DON'T INTERRUPT
7. Talk to scleritas, even if you previously did before
8. LINK ALL COMPANIONS, head into the temple like normal, and head over to Orin

DURGE Evil Ending (if you want to go this way):
Warning, this solution selects the final flag at the end of the questline to set you on the evil path. Do not use this unless you are ready to have the  DURGE quest set to basically complete.

https://forums.nexusmods.com/index.php?/topic/13136364-respec-appearance-edit-lite/page-215#entry127441353

Alternatively, you should be able to use the script extender console, select your DURGE character, and do SetFlag("3e081f26-3eb2-43c8-8c86-6200e464e8a9", GetHostCharacter(), 0, 1)

SetFlag("904c45e0-bb06-40ed-b5d7-4f1c851b9d86", GetHostCharacter(), 0, 1)

DURGE Good Ending (if you want to go this way):
Warning, this solution selects the final flag at the end of the questline to set
you on the good path. Do not use this unless you are
ready to have the DURGE quest set to basically complete.

SetFlag("885a6052-a198-4e01-b153-72e3867e4faa", GetHostCharacter(), 0, 1)

SetFlag("74944ac3-1ea0-4eae-9653-1f1319f8646b", GetHostCharacter(), 0, 1)

Save Orin's Victim Fix (Non Dark Surge) - Victim Companion keeps following you
Reload the save before killing Orin and follow these steps.

1. Set “Autoselect character after combat” to “off.”
2. Ungrouped Tav from the rest of the party.
3. As Tav, jump off the arena, to death.
4. Kill Orin.
5. Then kill the rest of the enemies (the ones with Sanctuary).
6. The cutscene of Orin's death plays afterward.

Do NOT unlock the table where the companion was unconscious until after the fight.
Do NOT loot Orin until AFTER the cutscene.

"Hesitating" when trying to use tadpole powers:
Select your character that has this issue and use this command in the console
SetTadpoleTreeState(GetHostCharacter(), 2)

Stuck on the goblin bridge cutscene OR Artifact disappearing from your inventory:

Osi.PROC_GLO_InfernalBox_SetPlayerOwner(GetHostCharacter())
Osi.PROC_GLO_InfernalBox_MoveBoxToCharacter(GetHostCharacter())
Go to camp, have shadowheart in your party  (attached to main character if in MP), select her, run the console commands, then long rest.  Then  when you go back to cross the bridge the cutscene should play as normal.

Origin Character Won't Talk To Me:
Select the character that won't talk to you, and use this command
Osi.DB_ObjectCountHelper:Delete(GetHostCharacter(), "GEB_BusyDialog", -1)

Or, try these commands in order
Osi.DB_InteractiveDialogSpeaker:Delete(nil, GetHostCharacter())
Osi.DB_CantTalk_IgnoreStatusesDead:Delete(GetHostCharacter())
Osi.DB_CantTalk_IgnoreStatuses:Delete(GetHostCharacter())


If that character isn't in your party, instead of GetHostCharacter(), please use one of the UUIDs associated with the character (include the quotation)

    "S_Player_Karlach_2c76687d-93a2-477b-8b18-8a14b549304c"
    "S_Player_Minsc_0de603c5-42e2-4811-9dad-f652de080eba"
    "S_GOB_DrowCommander_25721313-0c15-4935-8176-9f134385451b" -- Minthara
    "S_GLO_Halsin_7628bc0e-52b8-42a7-856a-13a6fd413323"
    "S_Player_Jaheira_91b6b200-7d00-4d62-8dc9-99e8339dfa1a"
    "S_Player_Gale_ad9af97d-75da-406a-ae13-7071c563f604"
    "S_Player_Astarion_c7c13742-bacd-460a-8f65-f864fe41f255"
    "S_Player_Laezel_58a69333-40bf-8358-1d17-fff240d7fb12"
    "S_Player_Wyll_c774d764-4a17-48dc-b470-32ace9ce447d"
    "S_Player_ShadowHeart_3ed74f06-3c60-42dc-83f6-f034cb47c679"

Long Rest Stuck:
Try this command

Osi.PROC_CheckPartyFull()
or, as a last resort, this one

RemoveStatus(GetHostCharacter(), "LONG_REST", "")


Wyll Reverts Back after Devil Form:
Use this console command to make Wyll human once more, and thus, editable

Osi.RemoveTransforms("S_Player_Wyll_c774d764-4a17-48dc-b470-32ace9ce447d")
Curse Monk Affliction is Back:
Resculpt again

Pixie Shield is missing after resculpting
Select your character and run this console command

Osi.ApplyStatus(GetHostCharacter(), "GLO_PIXIESHIELD", -1, 0, GetHostCharacter())
You must gather your party before venturing forth:
Dismiss everyone, resculpt MC, try again

Ketheric Netherstone Portal Issue:
Give the netherstone to a companion and then proceed through the portal as normal.

Character can't be targeted or doesn't seem to be the host anymore or character dying on sneak
Select your original pre-resculpted character and use this
print(Osi.GetFaction(GetHostCharacter()))

You'll get an output from that, copy that output, select the character that doesn't work, and use this console command. Replace where I put THEOUTPUTHERE with what you got from the previous command

Osi.SetFaction(GetHostCharacter(), "THEOUTPUTHERE")
And then to add the AVATAR tag, use this
Osi.SetTag(GetHostCharacter(), "306b9b05-1057-4770-aa17-01af21acd650")
Then, add these DBs
Osi.DB_Avatars(GetHostCharacter())
Osi.DB_PartyMembers(GetHostCharacter())

Osi.DB_Players(GetHostCharacter())

Another party member is taking priority in dialogues
Dismiss all of your party members and re-add them to the party