Update 2018-10-10: I have just tested the ENB with wesp's Unofficial Patch 10 and it seemed to work OK.

The VTMB ENB was a little messed up, so I took a look at using another source-engine ENB, the one for HL2.

What i was trying to emulate with this ENB config was a darker/neon look, thinking Bladerunner/Cyberpunk. I've only spent a few hours messing around with it.

Info:

• This includes sweetFX, so it might override your configs
• ENB: Colour correction is is set to provide higher levels of colour, dark areas are made much more dark
• ENB: Anisotropic filtering is enabled, there is a noticable difference, go and stand on a road and look into the distance
• ENB: Bloom is on, it is set to look sort of "smokey"
• ENB: Water Effects: The HL2 ENB water effect doesn't work, it actually screws up some lights, so i have left it off
• ENB: Depth of field is currently off because I don't like it all that much
• ENB: Anti-Aliasing is on, you may need to turn it off if you are doing this already via your video card
• SweetFX: HDR is on
• SweetFX: Lumasharpen is on
  

Install

• Just extract this .zip into the same directory as your vampire.exe
  

Notes

• Nexus user Frolich has pionted out that to take screenshots you should try using the built in ENB screenshot capabilities to catch all the post-processing effects
• Nexus user doyoume has noted that Gangrel beast vision might be too dark. Use Shift-F12 to toggle the ENB effect on and off if you have the same problem.
• There's some help here for people who are having issues with Windows 10: https://www.nexusmods.com/vampirebloodlines/mods/54
  

Credits:

• Boris Vorontsov for ENB Series
• CeeJay for SweetFX 
• Thanks to Nexus user Frolich for his screenshots