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Installation:
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I recommend you use a mod manager like NMM or the Mod Organizer to install mods. If installing manually, extract the archive contents into '.../data/'.

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Updating:
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1) Dismiss any hirelings from this mod that you have recruited.
2) Go into an interior cell with no NPCs, and make a new save game.
3) Uninstall the old version of the mod using the mod manager you installed it with. If uninstalling manually, delete 'Inconsequential NPCs.esp' and 'Inconsequential NPCs.bsa' from '.../data/'.
4) Install the new version of the mod.

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UnInstallation:
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1) Dismiss any hirelings from this mod that you have recruited.
2) If you have recently procured the...'services' of a 'flower girl' or a 'skooma addict', wait for the 'Relaxed' effect to wear off (it lasts one in-game hour, check your character's 'active effects' tab).
3) Make a new save game in an interior cell with no NPCs.
4) Uninstall using the same mod manager you installed it with. If uninstalling manually, delete 'Inconsequential NPCs.esp' and 'Inconsequential NPCs.bsa' from '.../data/'. That's it.