One thing I hated about this game is all the information I wanted such as health was in the corner of the screen and I had to take my eyes off the fight to check my health.

As you can see in the screenshot I moved most of the hud to surround the cross hair so I can see them without moving my eyes so far from the cross hair.

About the screen shot. I made the hud items that i didn't change invisible, so you can see the new layout. they are still visible in the game and in the same place like normal.

Installation

Mod manager
Download http://www.nexusmods.com/fallout4/mods/10654/?
Activate DEF_HUD
Activate tweaked hud and overwrite when asked to.

Manual
Download http://www.nexusmods.com/fallout4/mods/10654/?
Put interface folder in Data folder.
Download and open tweaked hud.
Put data folder in fallout 4 folder or interface folder in data folder.
Overwrite when asked to.